BCRB 2018

Consequential late effects (CLE): Mechanisms

early radiation effect

Epithelium

additional trauma

Endothelium Fibroblasts Parenchyma

late radiation effect

modified from: Dörr and Hendry, Radiother. Oncol. 61, 2001, 223-231

ESTRO BCR Course / Pathogenesis of NT effects – W. Dörr