BCRB 2018
Dose fractionation: LQ formalism
a/b -value - early effects / experimental data
Ref.
a/b -value [Gy] -
Tissue/reaction
Epidermis
Desquamation
Douglas and Fowler 1976 Joiner et al. 1983 Moulder and Fischer 1976 Ruifrok et al. 1994
9.1-12.5 8.6-10.6 9-12 49.6 [42.2;58.6] 7.9 [1.8;25.8] 10.8 7.4 16.4 [14.6;18.2] 11.6 [6.8;18.9] 11.9 [7.4;20.2]
Oral mucosa
Ulceration
Ang et al. 1985 Moses and Kummermehr 1986 (Reanalysis)
Scalliet et al. 1987 Stüben et al. 1991 Dörr et al. 1993 Nickstadt and Dörr, unpublished
Intestine
Crypt survival
Withers et a. 1976 Thames et al. 1981 Tucker et al. 1983
6.0-8.3 6.6-10.7 8-9 13.3 9-13-
Huczkowski and Trott 1984 Tucker and Denekamp 1984 Dörr and Schultz-Hector 1992 Dörr 1995
Weight loss
Urinary bladder Impaired function
13.9 [8.4;24.6] 11.0 [7.5;16.1]
Testis
clon. survival
Thames and Withers 1980
12-13
ESTRO BCR Course / NT radiosensitivity and fractionation – W. Dörr
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