Vetoryl brochure 2019

“Recent research at Glasgow and elsewhere has shown that the results of the ACTH stimulation test do not adequately indicate over- or under-dosing in dogs being treated with trilostane and therefore are not reliable for monitoring purposes. Pre-pill serum or plasma cortisol has been shown to be superior, though not optimal, in detecting a trilostane overdose and shows better correlation with the clinical signs. If used, cortisol measurements should be performed by the same laboratory and the laboratory should be conducting regular rigorous quality assurance (e.g. by participating in the ESVE scheme). Dogs should be as calm as possible before sampling. Sampling should be performed within 2 hours of the normal dosing time of the patient. Regardless of the chosen monitoring method, all results need to be interpreted with close regard to the clinical picture of treated patients when making trilostane-dose alteration decisions.”

ESVE Project ALIVE consensus statement, September 2017

Restore life and vitality