CROI 2016 Abstract eBook

Abstract Listing

Poster Abstracts

participants (OR = 1.29, 95% CI: 0.97-1.73). These associations were reduced after adjustment for prior HIV testing, indicating that differences in accuracy of self-report were largely due to differences in testing. Conclusions: The majority of participants were willing to share their HIV status, and false negative reports were largely explained by lack of testing or awareness of status, strongly suggesting that HIV stigma has retreated in this setting. In HIV interventions where testing is not feasible, self-reported status should be considered as a routine alternative to establish status because of the very high PPV and NPV.

908 Demographics and HIV Care Among New Yorkers LivingWith HIV by Diagnostic Cohort Laura Kersanske 1 ; Graham Harriman 1 ; LuciaV.Torian 2 ; Sarah L. Braunstein 1 1 New York City DHMH, Queens, NY, USA; 2 New York City Dept of Hlth, Long Island City, NY, USA Background: While HIV diagnoses in New York City (NYC) have been steadily decreasing over time, the city continues to have a large epidemic with over 2,500 new diagnoses each year. We characterized the demographics and clinical care indicators of all people living with HIV (PLWH) in NYC in 2013 by diagnostic cohort. Methods: Data on all NYC PLWH as of 12/31/2013 were acquired from the NYC HIV Surveillance Registry. PLWH were categorized into the following diagnostic cohorts based on year of HIV diagnosis: 1981-1984, 1985-1989, 1990-1994, 1995-1999, 2000-2004, 2005-2009, and 2010-2013. Demographics and clinical care indicators of these cohorts, including CD4 intervals and viral load (VL) suppression for those in care, were explored. Persons were considered in care if they had at least one HIV VL/CD4 in 2013. Results: There were 100,992 people diagnosed and presumed to be living with HIV in NYC as of 12/31/2013. Of these, 450 were diagnosed in 1981-1984, 7,955 in 1985-1989, 17,792 in 1990-1994, 22,789 in 1995-1999, 21,429 in 2000-2004, 18,699 in 2005-2009, and 11,878 in 2010-2013. The majority of PLWH in each diagnostic cohort were male, younger at diagnosis (20-39 years old), and classified as men who have sex with men. Race/ethnicity distributions differed by cohort. The largest proportions of PLWH from the earlier cohorts were white, while the largest proportions from the more recent cohorts were black. Viral suppression rates for PLWH in care in 2013 ranged from 71-82% across cohorts. Highest suppression was seen for those with a high CD4 count in 2013 (e.g., 80-91% for those with CD4 ≥500 cells/µL vs. 37-56% for those with CD4 <200 cells/µL) (Figure). Within CD4 intervals, there were slightly higher rates of viral suppression in the earlier diagnostic cohorts (e.g., 91% for 1981-1984 diagnoses vs. 80% for 2010-2013 diagnoses with CD4 ≥500 cells/µL) (Figure). Conclusions: Diagnostic cohorts of NYC PLWH in 2013 had similar distributions by sex, age at diagnosis, and transmission risk. They differed by race/ethnicity, though, reflecting the need to address health inequities among people at risk for and newly diagnosed with HIV. Viral suppression rates for PLWH in care were relatively high, regardless of diagnostic cohort. When examined by CD4 interval in 2013, the earlier diagnostic cohorts had higher suppression rates, possibly reflecting a survival advantage or additional time to initiate and remain on treatment. Additional research exploring resilience among earlier diagnostic cohorts is needed.

Poster Abstracts

382

CROI 2016