AOAC SPIFAN Stakeholder Panel (August 25, 2018)

First Action Recommendations

Nestle method: • Applicable or not applicable matrices • SPE confirmatory step for low level GE findings near the level of concern • Additional spike levels or incurred samples at higher level • Liquid concentrate to discuss applicability of the method

SGS method: • Address system suitability

• Verify the purity of the labelled standard with every run/batch • Verify the response factors over the analytical range to demonstrate linearity on every system • Written in AOAC format (missing steps, safety section)

First to Final Action Recommendations

Nestle method: • Consider use of GC-MS (single quad) • Include at least 1 matrix to be cleaned by the SPE procedure in the collaborative study • Use the SPIFAN kit in the collaborative study • Consider using a reference material for oil (for lab qualification) • Method feedback SGS method: • Consider use of GC-MS/MS • Use external multi-point calibration in the collaborative study & calculate the results using both single-point internal calibration and multi-point external calibration • Use the SPIFAN kit in the collaborative study • Consider using a reference material for oil (for lab qualification) • Method feedback