AOAC ISPAM Stakeholder Panel Meeting Book (August 26, 2018)

Action Item #1-A

1.1

bias ɴ-ETI lower ɴ-ETI upper

0.0

0

1

2

3

4

5

6

AL AL

ALs ALs

-1.1

Comparison

y = 0.9933x - 0.01

Large s for alternative and reference. No bias.

0.0 1.0 2.0 3.0 4.0 5.0 6.0

Initial AP Æ reject Current AP Æ accept

Alternative

0.0

1.0

2.0

3.0

4.0

5.0

6.0

Reference

Action Item #1-A

0.5

bias ɴ-ETI lower ɴ-ETI upper

0.0

0

1

2

3

4

5

6

AL AL

ALs ALs

-0.5

Comparison

y = 0.9894x + 0.3849

0.0 1.0 2.0 3.0 4.0 5.0 6.0

Small s for alternative and reference. Large bias.

Alternative

Initial AP Æ accept Current AP Æ reject

0.0

1.0

2.0

3.0

4.0

5.0

6.0

Reference