Basic Training 4th Annual ICP Conference

Fundamentals of Method Validation

Outline

• Purpose of Validation

Validation Characteristics 1. Specificity 2. Linearity 3. Range

• Types of Validations

4. Accuracy 5. Precision 6. Limits

• Characteristics • Definitions

a. Detection b. Quantification

• Suggestions/Guidelines • Examples

7. Robustness