Vitamins and Nutrients
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5-HTP (5-hydroxytryptophan) Snapshot Monograph
Nutrient name: 5-Hydroxytryptophan (5-HTP)
Most Frequent Reported Uses: Used to help maintain healthy serotonin levels.
Functions/Clinical Efficacy: 5-hydroxytryptophan (5-HTP) is an amino acid that is the precursor of the neurotransmitter serotonin and is made from L-tryptophan. Influences the synthesis of melatonin Reported to increase levels of brain dopamine and norepinephrine. Influences activities controlled by serotonin, which include regulation of
Helps to regulate mood, impulse control (aggression and obsessive behavior), appetite (food cravings), and sleep.
mood (anxiety and depression), impulse control (aggression and obsessive behavior), appetite (food cravings), pain control and sleep. Administration of 5-HTP as a dietary supplement has been reported to decrease the urinary excretion of serotonin.
Dosage Range: Health Maintenance: 50-100mg, one to three times a day. Clinical Use: 50-200mg, one to three times a day.
Symptoms of Depletion: Studies on deficiency of 5-HTP have not been conducted. A deficiency of serotonin may cause symptoms of anxiety, depression and sleep disturbances.
Toxicities, Warnings and Interactions: 5-HTP has been reported to occasionally cause gastrointestinal upset.
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