AOAC SPIFAN Stakeholder Program Meeting Book (March 17, 2021)

AOAC SMPR 2021.XXX; Version 7; February 17, 2021 1 2 Method Name: 3

Determination of Chlorate and Perchlorate in Baby Foods, Infant/Adult Formulas and Their Ingredients

4 5 6 Approved by: Stakeholder Panel for Infant Formula and Adult Nutritionals 7 Final version date : 8 Effective date: 9 10 11 Intended Use: Surveillance and Monitoring by Trained Technicians

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1. Applicability:

Determination of chlorate and perchlorate in baby foods, infant/adult formulas and their

ingredients (see Table 3).

2. Analytical Technique:

Any analytical technique that meets the following method performance requirements is

acceptable.

3. Definitions:

Accuracy 1

The closeness of agreement between the average of an infinite number of replicate

measured quantity values and a reference quantity value.

Limit of Quantitation (LOQ)

The minimum concentration or mass of analyte in a given matrix that can be reported as a

quantitative result.

Repeatability

Variation arising when all efforts are made to keep conditions constant by using the same instrument and operator and repeating during a short time period. Expressed as the repeatability standard deviation (SD r ); or % repeatability relative standard deviation

(%RSD r ).

Reproducibility

The standard deviation or relative standard deviation calculated from among-laboratory data. Expressed as the reproducibility relative standard deviation (SD R ); or % reproducibility

relative standard deviation (% RSD R ).

Adult/Pediatric Formula

Nutritionally complete, specially formulated food, consumed in liquid form, which may constitute the sole source of nourishment, made from any combination of milk, soy, rice, whey, hydrolyzed protein, starch, and amino acids, with and without intact protein.

1 Corresponds to the VIM definition for “trueness”.

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