AOAC SPIFAN Stakeholder Program Meeting Book (March 17, 2021)

A1/A2 Beta- Casein Testing

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A2 Beta-Casein Testing Overview

X No consensus on “A2 Milk” definition X Reference materials and purity standards undefined

X Test methods target two different analyte definitions: 1. Genetic

о Genetic testing and isolation of herd (A2A2) to acquire A2 milk о Effective for verifying commodity but not finished IF product (risk of cross-contamination in manufacturing) 2. Protein Milk or Milk Products containing E -casein о Target A1-type or A2-type protein о Target BCM-7 8