AOAC SPIFAN Stakeholder Program Meeting Book (March 17, 2021)

A2 Quantification in Infant Formula A2-type beta-casein A1-type beta-casein

X Capillary Zone Electrophoresis (AOAC poster)

Challenges, revisited

X Reference Standards

X No certified reference standard X Mixture of A1-type, A2-type beta-casein (most)

X Target level:

X Define “A2-milk” X Quality parameter (no agreement on exposure limits)

X What type of measurement?

X A1 beta-casein as a contaminant? X %A1 beta-casein/total casein X %A2 beta-casein/total casein