Hematological Malignancies

EORTC 20981: Rituximab maintenance vs observation in relapsed FL

CHOP every 21 days

R A N D O M I

R A N D O M I

Observation

maximum 6 cycles Rituximab + CHOP every 21 days maximum 6 cycles

CR PR

Rituximab maintenance*

Z E D

Z E D

*375mg/m 2 every 3 months for 2 years or until relapse

van Oers MHJ, et al. JCO 2010; 28:2853–2858