Hematological Malignancies

UNFOLDER

6 x CHOP- 21 + RT (Bulk, E)

CD20 + DLBCL IPI=1

6 x CHOP- 21 + no RT

Random 2x2 Factorial Design

&/or Bulk

6 x CHOP- 14 + RT (Bulk, E)

6 x CHOP- 14 + no RT