APAC SPSFAM Mid Year 2016
SMPR Key Points
• Repeatability ‐ Variation arising when all efforts are made to keep conditions constant by using the same instrument and operator and repeating during a short time period. Expressed as the repeatability standard deviation (SDr); or % repeatability relative standard deviation (%RSDr). • Reproducibility ‐ The standard deviation or relative standard deviation calculated from among‐ laboratory data. Expressed as the reproducibility standard deviation (SDR); or % reproducibility relative standard deviation (% RSDR). • Recovery Factor ‐ The fraction or percentage of the analyte that is recovered when the test sample is analyzed using the entire method.
Comments Submitted (if any)
Kombucha SMPR: Comment 1
Kombucha SMPR: Comment 2
SMPR Comments for:
Kombucha
SMPRComments for:
Kombucha
Submitter"s
ArmenMirzoian
Submitter"s Name
Name
KathyStenerson
Submitter"s Email Address
Submitter"s EmailAddress
armen.mirzoian@ttb.gov
katherine.stenerson@sial.com
Organization
MilliporeSigma
Organization TTB
Typesof Comments
Typesof Comments
Technical
Technical
LineNumbers (If Applicable)
51
Line Numbers (If Applicable)
66‐67
Theanalytical range is toowide, that is if this refers toaworking range. Itwill bedifficult formostanalytical techniques tobe linear in thiswideofa range. Since the limit tobe considerednonalcoholic is0.5%ABV, goingup to2.8% really shouldnotbenecessary.
Comments (Justificationof Change(s))
Sigma‐Aldrich200ProofEthanol cannotbeusedasa referencematerialbecause it doesnotarrivewithcertificateofanalysis that indicatesexact concentrationof ethanol. It canbeused in some cases forpreparationof standardsonlyafteraccurate
Comments (Justification ofChange(s))
concentrationofethanol isdeterminedbymeansof specific gravity.
Proposed Change(s)
Reduce this range to .1% to1%ABV
Proposed Change(s)
Remove thementionof SigmaAldrich200proofethanolasa referencematerial
Chair /CSOResponse:
Chair /CSOResponse:
Thiswasdiscussedby theworkinggroup andamajorityof theworkinggroupmembersagreed to leave the Sigma‐Aldrichmaterialon the listbecause it isa veryhigh concentration (>99.5%)material that canbediluted to lower concentrationsatwhichanyminordeviations in the claimed concentrationdonotmatter. Perhapsaparenthetical statement to theeffect that “this productdoesnotcomewitha certificateofanalysis” canbeadded to the SMPR. This issue canbe re‐examinedwhen the StakeholderPanelmeets.
This iswhatwearehaving todo since theonly available reference standardwe can find isa1.0%. We areusing the200Proof fromAldrichand standardizing itusing theCertified1% standard.Sam
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