2019 Year 12 IB Extended Essays

Testis Brain Breast Bronchus Salivary glands Tongue Saphenous vein Coronary artery Stomach

Colon Pancreas Adipose tissue Prostate Coronary artery Skeletal muscle

Myocd

604.56

544.10

Jejunum Colon Prostate

Nkx2.5 Pitx2c

588.21 33.06

529.39 29.75

None Brain Skin

Colon Adipose tissue Skeletal muscle Tongue Bone Marrow Placenta

Oral Mucosa Oesophagus Jejunum

Smyd1

853.31

767.98

Skeletal muscle Jejunum Skeletal muscle Tongue White blood cells

Srf

86.14

77.53

Bone marrow Oocyte

Tbx5

189.49

170.54

None

Table 2: Average signal of heart muscle cells for each transcription factor and comparison to other tissue types (Embryonic and adult normal tissues) Transcription factor Other tissue types that have similar or higher signal value

Average signal of heart muscle cells 247.6 233.97 21.17

90% of Average signal of heart muscle cells

Baf60c

222.84

Brain Adrenal gland

Islet Monocytes

Gata4 Hand2

210.57 19.05

Ovary

Oocyte Testis intersitial Brain

Breast Skeletal muscle Tongue Placenta

Hopx

112.77

101.49

Significantly lower expression in heart compared to other tissues

Hrt2

105.93

95.34

Brain Dorsal root/ trigeminal ganglion Tongue

Isl1

19.37

17.43

Significantly lower expression in heart compared to other tissues

Mef2c

42.3

38.07

Ovary Oocyte Testis Intersitial

Salavary gland Thyroid Prostate

17