SPIFAN Stakeholder Panel (September 23, 2017)

Analyte Definition-I

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Description of the analyte: Quantitative analysis of overall contents of 2-MCPD, 3-MCPD and glycidol, resulting from the separate or combined determination of free 2-MCPD and 2-MCPD esters, free 3-MCPD and 3-MCPD esters and glycidyl esters in all forms of infant, adult nutritionals, and/or pediatric formula (powders, ready-to-feed liquids, and liquid concentrates).

3-MCPD 3- mono -chloropropane-1,2-diol 3-Chloropropane-1,2-diol

glycidol (2,3-Epoxi-1-propanol)

2-MCPD 2- mono -chloropropane-1,3-diol 2-Chloropropane-1,3-diol

Analyte Definition-II

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Description of the analyte:

just examples, Bound analytes

FA

3-MCPD

FA

3-MCPD-1,2-bis-palmitoylester

FA FA

2-MCPD

3-MCPD-1-palmitoylester

Glycidol

FA

FA: all naturally occurring fatty acids “( ester) bound 2-/3-MCPD; (ester) bound glycidol ” : complex group of contaminants!

2-MCPD-1-oleoyl-3-stearoylester

Glycidylpalmitate

The terms “Bound 2-/3-MCPD” and “Bound Glycidol” should indicate that analytical reporting exhibits the contents of the core analytes but not the contents of the intact esters with higher molecular weights.