paediatrics Brussels 17

Ependymoma - Pathology

• Gd I – subependymoma and myxopapillary ependymoma • Gd II – Ependymoma • Gd III – Anaplastic ependymoma. Presence of hypercellular areas, necrosis, microvascular proliferation, high mitotic indices confer worse PFS Anaplastic histology + infratentorial location carries increased mortality risk in younger children Supratentorial location associated with higher mortality in older patients