paediatrics Brussels 17

Distant spread

• Approx 15% risk of spinal spread from post. fossa tumors • Spread occurs throughout the CSF pathways • Most often nodular • Very uncommon at presentation • Infratentorial tumors have higher risk of seeding than supratentorial tumors • More common with anaplastic ependymoma • Incidence of leptomeningeal spread varies with: Tumor grade (low grade 5%, high grade 10-15%) Tumor location (5% supratentorial, 10-15% infratentorial)