paediatrics Brussels 17

Table 1. Clinical and salvage treatment information for study patients ( Continued )

RT2 irradiation sites

Maximal reirradiation dose (Gy) and site

Resection or metastasectomy results

RT2 failure

Interval RT1 RT2 (mo)

RT age (Y)

CSI dose (Gy)

Reirradiation volume

Lesions/ surgery sites

Patient

Site 1 (Gy)

Site 2 (Gy)

Site 3 (Gy)

6.6 39.6 4 th ventricle (54.0)

25

CSI

1/1

NTR

29.9

—

— Cerebellum/stem (113.4) — Cerebellum/stem (113.4)

5.1 39.6 4 th ventricle (54.0)

26

CSI

1/1

GTR

35.7

—

27 28

CSI CSI

1/1 4/3

GTR STR

4.2

5.4 39.6 L36 S1 (59.4) 5.8 39.6 Lateral ventricles (59.4) 4.7 39.6 Infundibular recess (54.0) 4.0 39.6 Lateral ventricles (59.4) 5.8 37.6 Frontal (55.8) 9.3 39.6 Foramen rotundum (54.0) 4.2 41.4 Lateral ventricle (54.0) 4.8 39.6 Ca update (59.4) 3.7 39.6 Sylvian fissure (59.4) 10.2 39.6 Cervicomodullary (57.6) 13.3 39.6 T6 (54)

—

— Cerebellum/stem (99.0)

13.0

Conus (54)

Sacrum (59.4) Cerebellum/stem (99.0) Metastases

29

CSI

1/1

GTR

22.3

—

— Cerebellum/stem (99.0)

30

CSI

3/1

GTR

20.5

—

— Cerebellum/stem (99.0)

31 32

CSI CSI

2/2 3/3

GTR GTR

32.5 23.1

Finecal sac (57.6)

— Cerebellum/stem (93.6)

Ependymoma reirradiation d T. E. M ERCHANT et al . 91

L1 (54.0)

C7 (52.2)

Parietal (93.6)

33 34 35 36 37

CSI CSI CSI CSI CSI

1/1 1/1 5/3 1/1 2/2

GTR GTR GTR GTR GTR

23.6 24.3 25.3 28.0 43.7

—

— Cerebellum/stem (99.0) — Cerebellum/stem (99.0) — Cerebellum/stem (99.0)

T12 (54.0)

—

— Cerebellum/stem (99.0) Metastases

Conus (57.6)

— Parietal (93.6)

Metastases

38

CSI

1/1

STR

63.3

8.5 39.6 Fontal (59.4)

—

— Cerebellum/stem (99.0)

Abbreviations: SRS = stereotactic radiosurgery; CSI = craniospinal irradiation; NTR = near-total resection; GTR = gross total resection; STR = subtotal resection; RT = radiation therapy; RT1= initial radiotherapy; RT2 = reirradiation; CP = cerebellopontine.