2018 August 26 SPSFAM Book

Mycotoxin Analysis using LC-MS

Kai Zhang US Food and Drug Administration Center for Food Safety and Applied Nutrition

2018 AOAC Annual Meeting Toronto, Canada

What are Mycotoxins?

“Mycotoxins are toxic metabolites produced by certain fungi that can infect and proliferate on various agricultural commodities in the field and/or during storage.”

Source: FDA/COMPLIANCE PROGRAM GUIDANCE MANUAL/Chapter 07 – molecular biology and natural toxins

Aflatoxins ( Aspergillus flavus and parasiticus ) Ochratoxins A ( Penicillium and Aspergillus ) Citrinin ( Penicillium citrinum ) Ergot Alkaloids ( Claviceps ) Patulin ( P. expansum, Aspergillus, Penicillium , and Paecilomyces )