2018-19 Section 7-Neoplastic and Inflammatory Diseases of the Head and Neck eBook

Research Original Investigation

Epidemiology and Treatment of Malignant Submandibular Gland Tumors

Figure. Overall and Disease-Specific Survival of Patients With Submandibular Gland Tumor Using Kaplan-Meier Analysis

Overall survival for entire cohort A

Disease-specific survival for entire cohort B

1.0

1.0

0.8

0.8

0.6

0.6

0.4 Survival

0.4 Survival

0.2

0.2

0

0

0

100

200 300 400

500

0

100

200 300 400

500

Time, mo

Time, mo

No. at risk

No. at risk

2622

712

217

75

23

2182

638

202

71

23

Overall survival stratified by stage at presentation C

Disease-specific survival stratified by stage at presentation D

Stage I Stage II Stage III Stage IV

1.0

1.0

Stage I Stage II Stage III Stage IV

0.8

0.8

0.6

0.6

0.4 Survival

0.4 Survival

0.2

0.2

0

0

0

100

200 300 400

500

0

100

200 300 400

500

Time, mo

Time, mo

No. at risk Stage I

No. at risk Stage I

435 293 420 528

136

31 21 21

4 3 7 1

0 0 0 0

370 247 332 430

123

20 20 20

3 3 5 1

0 0 0 0

Stage II Stage III Stage IV

Stage II Stage III Stage IV

83

73 98 39

108

46

5

4

Overall survival stratified by histologic subtype E

Disease-specific survival stratified by histologic subtype F

1.0

1.0

Squamous cell carcinoma Adenocarcinoma Adenoid cystic carcinoma Mucoepidermoid carcinoma

Squamous cell carcinoma Adenocarcinoma Adenoid cystic carcinoma Mucoepidermoid carcinoma

0.8

0.8

0.6

0.6

0.4 Survival

0.4 Survival

0.2

0.2

0

0

0

100

200 300 400

500

0

100

200 300 400

500

Time, mo

Time, mo

No. at risk Squamous cell carcinoma Adenocarcinoma Adenoid cystic carcinoma Mucoepidermoid carcinoma

No. at risk Squamous cell carcinoma Adenocarcinoma Adenoid cystic carcinoma Mucoepidermoid carcinoma

475 360 945 443

53 81

8

1 6

0 1

357 289 833 373

45 72

7

1 6

0 1

20

19

346 133

124

51 12

19

319 113

118

48 12

19

41

1

35

1

JAMA Otolaryngology–Head & Neck Surgery October 2015 Volume 141, Number 10 (Reprinted)

jamaotolaryngology.com

Copyright 2015 American Medical Association. All rights reserved.

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