ESTRO GUIDE 2017

PRE-MEETING COURSES

CLINICAL PRE-MEETING COURSE Patient Reported Outcome Measures (PROMs) in radiotherapy research and clinical practice

FRIDAY 5 MAY 2017 Course directors: T. Holch (UK) and C. Grau (DK)

Session 3: Implementation in radiotherapy research and clinical practice in different cancers: • REQUITE study (radiogenomics) • Prostate lung cancer groups

COURSE AIM To provide an overview of the current and potential future roles of PROMs in radiotherapy research and routine care settings. LEARNINGOBJECTIVES • To assess the role of PROMs in clinical practice and within clinical trials. • To evaluate the use of PROM-basedmodels to predict patient risk of toxicity after radiotherapy and ion beam therapy. • To examine radiotherapy dose-volume relationships involved in normal tissue complication probability (NTCP). WHO SHOULD ATTEND? Clinicians, allied health care professionals and re- searchers interested in: • Improving their knowledge of the current and future role of PROMs • Improving patient outcomes in radiotherapy • Developing models predicting risk of radiotherapy toxicity. CONTENT Session 1: The PROMs value in cancer care: • Improved doctor-patient communication • Improved outcomes. Session 2:What are themethodological and practical challenges associated with the collection and use of PROMs? • Selection of measures, time points; electronic vs paper • Translation into different languages • Patient understanding • Non-compliance.

• Head and neck • Gynaecological.

Session 4: Correlating dose distribution and PROMs Modelling NTCP relationship to CTCAE and why PROs might be better validated evidence of change from baseline Session 5: Collection of electronic patient reported outcomes (ePROMs) • Feasibility of completion during and after treatment Session 6: Standard of PROM reporting in trials PRO Consort guidelines applied to clinical trial re- porting Session 7: Future directions and research priorities in the development of PROM measures and the ap- plications of PROM data. • Economics, relating PROMs to dose distribution • Scalability of ePROM systems • Cat vs traditional questionnaires. Session 8: Discussion: How to integrate PROMs into clinical practice Practical ideas towards implementation. • Early evaluation indicators • Patient and staff acceptance • Longitudinal follow up.

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ESTRO CONFERENCES