129th AOAC Annual Meeting & Exposition Preliminary Program

SCIENTIFIC SESSIONS – WEDNESDAY

Analytical Roundtable for Regulators and the Regulated: Analytical Laboratories and the Dietary Supplements cGMP Challenge Current Good Manufacturing Practice regulations for Dietary Supplements have now been in place since 2007, and full compliance has been required since 2010. Several years of theoretical discussions are in the process of becoming informed by actual laboratory practice and FDA enforcement. This session will engage the audience in an interactive panel discussion with analysts from supplement company’s in-house laboratories, small and large contract laboratories, an innovative contract research organization, a botanical supplier dealing with FSMA requirements, and regulatory experts. The discussion is expected to be free- wheeling and will range from identity testing requirements, “reasonably anticipated contaminants”, standard operating procedures, “verification or validation”, and qualification of standards and reference materials. The ultimate goal of the session is to put manufacturers and contract labs in the same room so that contract labs can provide a breakdown of tests available and the average resources necessary to perform, manufacturers can provide a realistic picture of their available resources, and for regulatory experts to comment on the mandates of the regulation as related to resources. CO-CHAIR: Joseph Betz, National Institutes of Health CO-CHAIR: Amit Chandra, Amway R&D • Darryl Sullivan, Covance Laboratories Inc. • Aniko Solyom, GAAS Corporation • James Neal-Kababick, Flora Research Laboratories • Shauna Roman, RB Manufacturing LLC • Jana Hildreth, Synutra Pure, Ltd. • Steven Dentali, Herbalife • Catherine Rimmer, National Institute of Standards and Technology • Melissa Phillips, National Institute of Standards and Technology • Rupa Das, BI Nutraceuticals • Oral Poster Presentation Wayne Wolf, Agricultural Research Service (Retired) TDRM/AOAC Reference Materials-Methods Database

1:00 pm – 2:30 pm

Analyses of Carbohydrates and Dietary Fiber Carbohydrates are widely used in food and supplemental nutrition products as a major energy source, sweeteners, and for improving texture. Carbohydrates, such as dietary fibers, can also provide functional benefits. Unlike other nutrients, dietary fiber derives its nutritional value not from being digested and absorbed but remaining undigested while passing through the stomach and small intestine and being partially or fully fermented in the large intestine. With increasing consumer awareness and progressing regulations, specific and accurate analyses of carbo- hydrates, including simple sugars, complex digestible carbohydrates, and dietary fibers, are of great importance. While liquid chromatographic methods are widely used to quantify specific sugars and oligosaccharides, quantitative measurement of dietary fibers depends on measuring resistance to digestion. Key to dietary fiber methodology is accurately simulating the human digestion system, method reproducibility, and assuring capture and quantitation of the digestion resistant fraction of the food. This scientific session will provide an update on the use and analysis of carbohydrates and dietary fibers in food prod- ucts, as well as other technical considerations. CO-CHAIR: Kommer Brunt, Rotating Disc BV CO-CHAIR: Jon DeVries, Retired-Medallion Laboratories/ General Mills CO-CHAIR: Xun Yan, AMWAY • Kommer Brunt, Rotating Disc BV The Functionalities of the Various Carbohydrates Present in Our Daily Food • Yannis Vrasidas, Eurofins Enzymatic Characterization and Quantification of Non- Starch Polysaccharides in Food: Galactomannan as an Example • Barry McCleary, Megazyme International Ireland A Rapid Integrated Procedure for Measurement of Total Dietary Fiber • David Plank, Medallion Laboratories / General Mills Updating the Basic Technologies of Dietary Fiber Analyses

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September 27–30, 2015 |  Westin Bonaventure Hotel |  Los Angeles, California