2013 UC Merced Research Enterprise Book

Stem Cell Instrumentation Foundry

The mission of SCIF is to provide an open and versatile environment for the most promising stem cell projects.

S Stem cell research is an extraordinari- ly promising field of modern biology, yielding already fundamental discoveries on the nature of complex organisms and human medicine. The Stem Cell Instrumentation Foundry (SCIF) was created to provide stem cell scientists at UC Merced and throughout California access to the instruments, techniques and training necessary for carrying out advanced applications in stem cell research. The facility was created and is funded by a $4.35 million investment by the California Institute of Regenerative Medicine. The Foundry is housed in 4,260 square feet of research laboratory space pro- viding for human and mouse stem cell culture, flow cytometry, quantitative cell imaging, as well as Class 1000 and 100 clean rooms for micro/nano fabrication and workstations. What sets SCIF apart from analogous laboratories at other institutions is that it houses a range of microfluidics, nano-

cells – discoveries that will help research- ers further understand the molecular signals that influence the properties and behavior of stem cells. Advanced innovations resulting from this research will allow the development of new and revolutionary treatments for a wide array of human diseases. Leadership and Vision for SCIF As the director of SCIF, ANAND GADRE , Ph.D., MBA , oversees training and man- ages the equipment and other resources of the Foundry. Gadre has extensive col- laborations with other campus research- ers, and, in particular, shares his research interests in the areas of lab-on-a-chip systems, microfluidics stem-cell-based tissue engineering and biosensing. His vision for SCIF is that it will enhance the research experience for undergrad- uate and graduate students in their early academic careers – helping create future leaders in research – and serve as a hub for collaborations within the campus and with neighboring institutions.

technology and single-cell analysis-based systems. This enables researchers, many with no prior knowledge of micro/ nano techniques, to custom design their unique devices online to address their specific scientific needs and rapidly inte- grate these cutting-edge technologies into their experimental designs. SCIF is also equipped with advanced “collaboratory” technology, composed of integrated, tool-oriented computing and communications systems allowing researchers to access both online support and workshops, as well as connect with collaborating scientists. SCIF is also set up to allow for the development of new tools and approaches applicable to basic and applied research that will further advance the understanding of regenera- tive medicine. The mission of SCIF is to provide an open and versatile environment for the most promising stem cell projects.

The research conducted at the Foundry will enable new discoveries about stem

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