Palliative care 2016

Limited evidence for effectiveness of radiotherapy on bone quality or fracture risk

Fracture -> postoperative RT • Townsend et al, IJROBP 1995 • N= 64 • 53% vs. 11% (MV, P< 0.01) → function

Impending • Koswig et al, Strahlenther.Onc. 1999 • N= 107 • 8 Gy SF vs. 30 Gy / 10 fr. • Higher dose -> more recalcification

Groenen et al, R&O 2016, Willeumier et al. R&O 2016