Palliative care 2016

The Patchell-Study

randomized trial, stopped after interim analysis (Patchell, Lancet,

2005)

surgery plus 10 x 3 Gy (N=50) vs. 10 x 3 Gy alone

(N=51)

ability to walk after treatment: 42/50 (84%) vs. 29/51 (57%), p=0.001

maintaining ambulatory status for: median 122 vs. 13 days, p=0.003 Surgery only for selected patients (10-15%): KPS  70 , OS  3 mos., no paraplegia > 48 hrs., 1 spinal segment, no myeloma

• 10 years to accrue (not all eligible patients included?) •  10% more ambulatory patients than in other series • small number of patients (statistical power?)