Palliative care 2016

Opioiden ~ Respiratory depression?

Total n=661 ( % ) 460 (69.6) 423 (64.0)

Elderly n=341( % ) 255 (74.8) 232 (68.0)

Opioid naïve n=55( % )

Any adverse event General disorders

38 (69.1) 35 (63.6)

Nervous system disorders

23 (3.5)

16 (4.7)

2 (3.6)

Gastro-intestinal disorders

54 (8.2)

37 (10.9)

4 (7.3)

Psychiatric disorders

34 (5.1)

24 (7.0)

2 (3.6)

Respiratory system disorders

1 ( 1.8 )

9 ( 1.4 )

6 ( 1.8 )

Skin & appendages disorders 10 (1.5)

8 (2.3)

1 (1.8)

Urinary system disorders

7 (1.1)

6 (1.8)

0 (0) Menten 2003, PhD Thesis