2017_SBRT_Course Book

Pain control with conventional radiotherapy for bone metastases

# patients Fractionation Complete or partial pain response

Duration

Prince 1986

1 x 8Gy 10 x 3Gy 1 x 10Gy 5 x 4.5Gy

73% 64% 84% 89% 72% 69% 61% 53%

59% @ 3 mo 50% @ 3 mo Median 3.5 mo Median 3.5 mo Median 5 mo Median 6 mo Median 3.5mo Median 5.5 mo

288

Gaze 1997

280

Steenland 1999

1 x 8Gy 6 x 4Gy 1 x 8Gy 5 x 4Gy

1171

Roos 2005

272

• Pain response after conventional RT: • Pain control after 3 – 6 months:

~70% ~35%

ESTRO SBRT 2017 - Matthias Guckenberger

07.09.17

5

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OS in patients with vertebral metastases

Conventional radiotherapy

SBRT

Guckenberger submitted

Leithner Eur Spine J

• Favorable OS in selected patients • Contribution of SBRT?

ESTRO SBRT 2017 - Matthias Guckenberger

07.09.17

6

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