2017_SBRT_Course Book

DOSIS: a multi-center phase II trial

7

6

5

4

3

2

VAS pain score

1

0

prior RT End RT 1 week 2 weeks 3 weeks 4 weeks 5 weeks 6 weeks 3 months6 months9 months 12 months

Time

• Rapid, deep and durable pain reduction

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35

Painful vertebral metastases

Short life expectancy Conventional radiotherapy

Longer life expectancy SBRT radiotherapy

• ≤3mm GTV – SC • Osteolytic Hypofractionated SBRT

• >3mm GTV – SC • Osteoblastic

Single fraction SRS

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