2017_SBRT_Course Book

• Retrospective analysis of 32 patients treated with 2 (n=29), 3 (n=2) or 4 (n=1) SBRT courses SBRT for re-irradiation after SBRT

Toxicity grade III - V

Grade V bleeding: n=3 Ø All centrally located

Peulen Radiother Oncol 2011

Ø SBRT reirradiation for central recurrences strongly discouraged!

07.09.17 ESTRO SBRT 2017 - Matthias Guckenberger

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Recurrent NSCLC

Palliative intend

Potentially curative intend

Asymptomatic

Symptomatic

Peripheral

Central

Intermediate volume (<250cc)

< 40cc central overlap

> 40cc central overlap

Large volume (>250cc)

Small volume (<2-3cm)

Full-dose CF-RT

Full dose CF-RT

Reduced dose CF-RT

Reduced dose CF-RT

SBRT

No RT

10–15 x 3Gy

Ø A proposal for risk-adapted re-irradiation

07.09.17 ESTRO SBRT 2017 - Matthias Guckenberger

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