2017_SBRT_Course Book

Pre-SBRT risk assessment

Mizumoto Cancer 2008

/ SBRT Spine - Matthias Guckenberger

7

Dose & fractionation in DOSIS trial

Epidural disease: No epidural disease:

10 x 4.85Gy

EQD2 60Gy EQD2 60Gy

5 x 8Gy

Fractionation Scheme Spinal Cord + 1mm

5x 4 / 8

10x3/ 4.85

5x 4/ 7

10x3/ 4.85

23.75

35

0.1cm 3

20

30

Cauda Equina

25

37.5

0.1cm 3

20

30

Kidney

-

-

10

12

Bowel

24

37

1cm 3

-

-

Esophagus

30

40

1cm 3

-

-

Liver

-

12.5

17.5

/ SBRT Spine - Matthias Guckenberger

8