2017_SBRT_Course Book

Conclusions

Based on experimental observations: • Traditional models for cell survival after radiation may overestimate the cell kill (especially with high dose per fraction) • In addition to direct radiation cell kill, there may be indirect cell kill related to – (Vascular effects and) – Immune effects • Chemotherapy may enhance SBRT induced cell kill • Hypoxia should not be ignored; why not add nimorazole?