AOAC Food Fraud Initiative Meeting Book (August 28, 2018)

Non-Targeted Screening

• Variety of methodologies being explored – LC-MS/MS – NMR – Spectroscopic – XRF and other ones for certain matrices • Data analysis – Chemometrics – Principle Component Analysis – Customized software • Simple, general sample preparation • Select rapid, general analytical techniques • Identify matrix types for study – Use variety of matrix types – For each matrix • Label one as CONTROL • Remaining samples blindly labeled • One un-adulterated sample • Remaining with known economic adulterants Example of a Non-Targeted Analysis Study