MCPD-02 Reviewer Forms (July 19, 2018)

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Reviewer 8

Supporting Data • General Comment: - Method Optimization: MRM and method conditions have been mentioned in detail. • Performance Characteristics:

Analytical Range: Yes, covered as per SMPR for 2 & 3- MCPD (25- ≥1000)

LOQ : Has been determined and it is within acceptance limits.

Accuracy/Recovery: Has been determined and it is within acceptance limits.

Precision (RSD r

): Has been determined and it is within acceptance limits.

Reproducibility (RSD R

): Has been determined and it is within acceptance limits.

• System suitability: It has been performed as per the SMPR .

Were the recommendations/comments completed as requested by the ERP? Yes, All the recommendations were addressed except for few comments as given below: Recommendation for First Action Official Methods SM status: The method is good candidate to be proposed as AOAC official method of first action

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