Practice Update Neurology

VOL. 1 • No. 1 • 2016 ISSN 2206-4680

RESEARCH NEWS AND VIEWS FROM ELSEVIER

OPINION

. ..if you are really looking at the tumour tissue prior to your targeted approach, youwill probably get more out of the treatment than if you take a one-size-fits-all type of approach

Interleaving deep brain stimulation improves dyskinesias and parkinsonism

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Dr Wolfgang Wick

Interleaving stimulation has been shown to be most beneficial for dyskinesias and parkinsonism, with minimal improvement in reducing other adverse effects. This conclusion, based on results of a retrospective chart review, was presented at the American Academy of Neurology’s 68th Annual Meeting, from April 15 to 21. 3

GENERAL NEUROLOGY

“It may even be useful to determine if some of the approved drugs for treating HIV could be repurposed for controlling HERV-K replication” 5 Hemiparetic children participating in intensive, psychosocial rehabilitation programs can achieve sustained functional gains. Addition of CIMT and rTMS increases the chances of improvement 6 MULTIPLE SCLEROSIS Metformin and pioglitazone may be effective for the treatment of inflammation in MS, and this warrants further evaluation and future research 7

BRAIN CANCER What is the future of neuro-oncology? CONFERENCE AAN 2016 WEPOD Confirmed: The safety of pregnancy in women with epilepsy PREVAIL III A majority of Ebola virus survivors experience neurological symptoms 6 months after infection

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Progressive cerebellar atrophy and anti-NMDA receptor encephalitis JAMA Neurology Diffuse cerebral atrophy is reversible and does not imply a poor clinical outcome within the context of anti– NMDA receptor encephalitis. Further studies are warranted to determine whether progressive cerebellar atrophy can serve as a reliable prognostic marker for poor clinical outcome.

Anticholinergic use and cognition and brain atrophy in cognitively normal older adults JAMA Neurology The use of AC medication should be avoided in older adults if a suitable alternative is available due to the

High coffee consumption and decreased risk for multiple sclerosis Journal of Neurology, Neurosurgery, and Psychiatry The findings are in line with animal research results, and, keeping in mind the limitations intrinsic to this retrospective epidemiology design, suggest a protective role of coffee consumption for development of MS.

Deep brain stimulation of the ventral tegmental area for refractory chronic cluster

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headache Neurology This study supports that

VTA-DBS may be a safe and effective therapy for refractory

associated increase in brain atrophy and clinical signs of cognitive decline.

CCH patients who failed conventional treatments.

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