NVUS 2018 Annual Report

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0DUN 2QH ܈ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2018 OR ܆ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 )RU WKH WUDQVLWLRQ SHULRG IURP WR &RPPLVVLRQ ILOH QXPEHU 12986 7+(5$3(87,&6 ,1& ([DFW QDPH RI UHJLVWUDQW DV VSHFLILHG LQ LWV FKDUWHU

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19900 MacArthur Boulevard, Suite 550 Irvine, California (Address of principal executive offices)

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Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes ܆ No ܈ Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. Yes ܆ No ܈

Indicate by check mark whether the registrant: (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ܈ No ܆ Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S- T during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes ܈ No ܆ Indicate by check mark if disclosure of delinquent filers pursuant to Item 405 of Regulation S-K is not contained herein, and will not be contained, to the best of the UHJLVWUDQW¶V NQRZOHGJH LQ GHILQLWLYH SUR[\ RU LQIRUPDWLRQ VWDWHPHQWV LQFRUS orated by reference in Part III of this Form 10-K or any amendment to this Form 10-K. ܈ Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth FRPSDQ\ 6HH WKH GHILQLWLRQV RI ³ODUJH DFFHOHUDWHG ILOHU ´ ³DFFHOHUDWHG ILOHU ´ ³VPDOOHU UHSRUWLQJ FRPSDQ\ ´ DQG ³HPHUJLQJ JURZWK FRPSDQ\´ LQ 5XOH E -2 of the Exchange Act. Large accelerated filer ܆ Accelerated filer ܆ Non-accelerated filer ܈ Smaller reporting company ܈ Emerging growth company ܈ If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ց Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes տ No ց As of June 29, 2018 WKH ODVW EXVLQHVV GD\ RI WKH UHJLVWUDQW¶V PRVW UHFHQWO\ FRPSOHWHG VHFRQG ILVFDO TXDUWHU WKH DJJUHJDWH PDUNHW YDOXH RI WKH UHJLVWUDQW¶V FRPPRQ VWRFN held by non-affiliates was $47,021,457, based on the last reported sale price of such stock on the Nasdaq Global Market as of such date. As of March 22, 2019, the registrant had 9,434,243 shares of Common Stock, $0.001 par value per share, outstanding. DOCUMENTS INCORPORATED BY REFERENCE 3RUWLRQV RI WKH UHJLVWUDQW¶V GHILQLWLYH SUR[\ VWDWHPHQW IRU LWV 9 Annual Meeting of Stockholders, which the registrant intends to file pursuant to Regulation 14A with WKH 6HFXULWLHV DQG ([FKDQJH &RPPLVVLRQ QRW ODWHU WKDQ GD\V DIWHU WKH UHJLVWUDQW¶V ILVFDO \HDU HQG 'HFHPEHU 31, 2018, are incorporated by reference into Items 10, 11, 12, 13 and 14 of Part III of this Annual Report on Form 10-K.

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