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ERP Methods Book

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1 Table 16: Robustness study: Mean differences (log 10 ) and 95% confidence intervals between each treatment combinations and  2 the nominal test condition  3

Treatment combination a

Target Analyte 

Inoculation  Non‐Target  Organism c

1 

2 

3 

4 

N/A d

N/A

N/A

N/A

Klebsiella  oxytoca  (ATCC b 51817)

‐0.0110  (‐0.0962, 0.0743)  ‐0.0826  (‐0.1680, 0.0029) 

0.0011  (‐0.0690, 0.0711)  0.0371  (‐0.0441, 0.1184) 

0.0723  (‐0.0021, 0.1468)  0.0673  (‐0.0251, 0.1597) 

0.1111  (0.0314, 0.1908)  0.0913  (0.0091, 0.1735) 

Low Level 

High Level 

Non‐Target  Organism 

N/A 

N/A 

N/A 

N/A 

E. coli  (ATCC  8739)

0.0102  (‐0.1522, 0.1726)  0.0091  (‐0.0530, 0.0711) 

0.0424  (‐0.1346, 0.2194)  0.0606  (‐0.0176, 0.1389) 

0.0880  (‐0.0268, 0.2027)  0.0524  (‐0.0330, 0.1378) 

0.1333  (0.0218, 0.2448) 

Low Level 

High Level  0.1163  (0.0534, 0.1793)  a Treatment combinations: 1) 0.9 mL sample volume, 16 h incubation time; 2) 0.9 mL sample volume, 28 h incubation time; 3) 1.1 mL sample volume, 16 h  4 incubation time; 4) 1.1 mL sample volume, 28 h incubation time. Nominal test condition: 1.0 mL sample volume, 18–24 h incubation time.  5 b ATCC: American Type Culture Collection, Manassas, VA.  6 c Staphylococcus aureus ATCC 6538.  7 d N/A: Not applicable. Non‐target organism was not detected, producing an enumeration of <1. 

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December 6, 2018