Statistics Meeting Book (May 15, 2019)

Proficiency Test Study

• Carried out by NIST • Incremental in Sample = Matrix with single Concentration. (Matrix and Concentration are confounded.) • Analyte: Curcumin • Exemplar data is first two Samples for Curcumin • Each laboratory measured in triplicate

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Proficiency Test Study Data

Lab NIST O404 O407 O411 O416 O419 O433 O437 O446 O449 O455 A 11.26 9.71 12.19 10.76 10.22 8.78 10.93 11.59 10.87 B 11.30 9.71 12.92 11.17 9.99 8.92 10.65 12.10 10.63 C 11.41 9.73 12.61 11.20 9.82 9.16 10.76 11.00 11.01 Avg 11.04 11.32 9.72 12.57 11.04 10.01 8.95 10.78 11.56 10.84 SD 0.21 0.08 0.01 0.37 0.25 0.20 0.19 0.14 0.55 0.19 A 802 871 796 810 787 745 765 852 841 B 750 793 866 803 784 774 799 867 850 C 731 845 755 834 781 769 772 871 860 Avg 822 761 836 805 816 784 763 779 863 850 SD 11 37 40 56 16 3 15 18 10 9 Individual Results

Sample A: SRM 3299 Turmeric Rhizome (mg/g)

Sample B: SRM 3300 Tumeric Extract (mg/g)

NOTES: Units are mg/g. ‘A’, ‘B’, and ‘C’ are triplicate measurements. ‘NIST’ is the presumed correct value, based on many accurate measurements.

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copyright 2018 by Least Cost Formulations, Ltd., all rights reserved.