Quality Management 2017

Action limits - Proposed philosophy

Step 4:

Define the center of the true dose probability

distribution respectively.

as the lower and upper action limit ,

Prescribed dose

Probability distribution for the true dose

Dose (Gy)

is set to a minimum acceptable cure rate

TL

is set to a maximum acceptable complication rate

TL

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

Clinical tolerance limits

From Jörgen Olofsson (Dose Modeling and dose verification ESTRO COURSE)