Brain Tumours

MRI: ANATOMIC IMAGING AND PSEUDO-PROGRESSION

PSEUDO-PROGRESSION is a self-limited type of treatment-related tissue injury that is common in the first 3-6 months after TMZ and radiation therapy, and mimics tumor progression, but then stabilises and decreases (Brandsma D et al. Lancet oncol 2008)

Before RT+TMZ

Before adjuvant TMZ After 2 cycles adj TMZ

Differ from classic radiation necrosis, which can also mimics tumour progr but is typically more severe and delayed in onset.