AOAC-RI ERP Book Micro Jan 19 2017

Table 5. POD CP , POD CC , and dPOD CP Values for the Candidate Method (325 g Ground Beef 18 hr Enrichment Analyzed via the 3M TM MDA) and POD R , POD C , and dPOD C Values for Candidate Method vs. the Reference Method (325 g Ground Beef 18 hr Enrichment Analyzed via the USDA FSIS MLG Method 5.09)

95% CI

Method / Inoculation Level

Measure Value

POD CP POD CC dPOD CP POD CP POD CC dPOD CP POD CP POD CC dPOD CP

1.000 (0.5655, 1.000) 1.000 (0.5655, 1.000) 0.000 (-0.434, 0.434) 0.450 (0.2582, 0.6579) 0.450 (0.2582, 0.6579) 0.000 (-0.283, 0.283) 0.000 (0.000, 0.4345) 0.000 (0.000, 0.4345) 0.000 (-0.434, 0.434) 1.000 (0.5655, 1.000) 1.000 (0.5655, 1.000) 0.000 (-0.434, 0.434) 0.550 (0.3421, 0.7418) 0.450 (0.2582, 0.6579)

Candidate Method Screening vs. Confirmation High Level Inoculation

Candidate Method Screening vs. Confirmation Low Level Inoculation

Candidate Method Screening vs. Confirmation Un-inoculated

POD R POD C

Reference Method vs. Candidate Method High Level Inoculation

dPOD C

POD R POD C

Reference Method vs. Candidate Method Low Level Inoculation

dPOD C

-0.100 (-0.371, 0.194)

POD R POD C

0.000 (0.000, 0.4345)

Reference Method vs. Candidate Method Un-inoculated

0.000 (0.000, 0.4345) 0.000 (-0.434, 0.434)

dPOD C

POD CP , Probability of Detection for Candidate Method “Screening Stage” Positive Results; POD CC

, Probability of , Probability of

Detection for Candidate Method “Confirmation Stage” Results; dPOD CP Detection for Reference Method Confirmed Results; POD C

, POD CP

Minus POD CC

; POD R

, Probability of Detection for Candidate Method

Confirmed Results (i.e. Combined “Screening Stage” and “Confirmation Stage” Results); dPOD C , POD R Minus POD C . 95% Confidence Interval Values are Generated from the AOAC International POD Calculator.

CONFIDENTIAL INFORMATION Page 10 of 13