2016 Trumbull Protocol Book

Tranexamic Acid (TXA) Tranexamic Acid (TXA)

Action

Onset

Antifibrinolytic

Immediate 3 hour half-life

Indications Multisystem trauma with internal hemorrhage

Adult Dose 1 g mixed in 50 mL IV bag connected to 10 gtts/mL administration set, and administer over 10 minutes (1 drop per second)

Pediatric Dose Not indicated.

Contraindications Isolated traumatic brain injury, more than 3 hours since injury, patients < 15 years of age, nontraumatic shock

Adverse Reactions Hypersensitivity

Precautions Monitor for symptoms of severe allergic reaction and changes in vision

221

EMR

EMT

AEMT

Paramedic

Extended