2015 HSC Section 1 Book of Articles

Givens DJ, Buchmann LO, Agarwal AM, et al. BRAF V600E does not predict aggressive features of pediatric papillary thyroid carcinoma. Laryngoscope . 2014; 124(9):E389-E393. EBM level 4.............................................................................233-237 Summary: This article investigates the BRAF V600E mutation in pediatric papillary thyroid carcinoma (PTC). In adult papillary thyroid carcinoma, the BRAF V600E mutation predicts more aggressive disease. This study reveals that the BRAF V600E mutation is more prevalent than previously reported in pediatric PTC patients, but the mutation was not associated with aggressive clinical features in the pediatric population. Summary: This article summarizes the evaluation and management of neck masses in children. Neck masses are divided into three categories: developmental/ congenital, inflammatory/reactive, and neoplastic. Depending on the history of the neck mass, laboratory or imaging studies may be indicated. Management depends on what category the neck mass falls in and ranges from watchful waiting to antibiotic therapy, incision and drainage, or surgical excision. Tekes A, Koshy J, Kalayci TO, et al. S.E. Mitchell Vascular Anomalies Flow Chart (SEMVAFC): a visual pathway combining clinical and imaging findings for classification of soft-tissue vascular anomalies. Clin Radiol . 2014; 69(5):443-457. EBM level 5.......................................................................................................................244-258 Summary: This article provides an algorithm for the diagnosis, management, and treatment for vascular anomalies. The algorithm utilizes the classification system established by the International Society for the Study of Vascular Anomalies (ISSVA) separating the vascular tumors and vascular malformations along with the use of radiological studies to guide practitioners. Meier JD, Grimmer JF. Evaluation and management of neck masses in children. Am Fam Physician . 2014; 89(5):353-358. EBM level 5..............................................238-243