IGRT 2016 Madrid

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Early Breast Cancer: S ± XRT meta-analysis Total: 40 Prosp. Rand. Trials, N ≈ 20,000 (50% had N+ve disease), XRT treating breast/chest wall, SCF, AX, IM regions

Increased mortality with XRT ! - 30% Cardiac deaths

Difference = 4.8%

EBCT Collaborative Group. Lancet 2000

Radiotherapy

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