22 Penis Cancer

Table 21.2: Penis Carcinoma: Results of Brachytherapy

Authors

Pts N.

TNM stage

Treatments

Brachytherapy Survival % Local control %

Complications %

Akimoto (1) Chaudary (6) Delannes (9)

15 23 51

T1 8; T2 5; T3 2 T1 7; T2 7; Rec 9 T1 15; T2 28; T3 6 N0 43

BT ± EBRT BT alone BT S ± EBRT/N S ± EBRT/N BT ± EBRT BT alone S±EBRT/N BT alone 25; S+BT 6 BT alone 37

LDR mould interstitial LDR

DFS 74

80 78 86

PC 73 US 9

interstitial LDR AS 72

US 33; NC 18; PC 67

Gerbaulet (11,13) 109 T1 28; T2 54; T3 22; T4 11; Rec 4 – N0 89 BT

interstitial LDR DFS 74

82

US 15; NC 13; PC 82

Guedea (16) Kanfir (19)

16

T1 16; T2 5; T3 2

interstitial LDR DFS 79 interstitial LDR OS 55 CSS 85 interstitial LDR OS 69

87 84

Cpl 25; PC 87

145 T1 107; T2 18; T3 11; Tx 9 pN+ 17

US 24; NC 14; PC 80

Kiltre (20)

31

St I 27; St II4 N0 3

81

US 35; PC 81

Mazeron (22)

50

T1 9; T2 27; T3 14 N0 45

interstitial LDR DFS 74

78

US 16; NC 6; PC 14

Rozan (30)

259 T1 112; T2 97; T3 25 N0 191

BT alone 184 (A) EBRT±S+BT 75 (B) S±EBRT/N

interstitial LDR OS 66 CSS 88 DFS 78

85

LSE 53 PC: A 78; B 64

Suchaud (24)

53

T1 7; T2 32; T3 15 N0 37

BT alone 48 EBRT+BT 5

interstitial LDR

79

Cpl 28

ƒ Stage :

Rec : recurrence PN+ : pathological positive nodes BT : Brachytherapy EBRT : External Beam Radiotherapy Surgery

ƒ Treatments :

ƒ Complications :

US : urethral stenosis NC : necrosis PC : penis conservation Cpl : complications

ƒ Results :

AS : Actuarial survival

DFS : Disease Free Survival OS : Overall survival CSS : Cause specific survival