CPB Ljubljana 2018 course book

Comparison of POBT with reference centers

19 patients pT1-2 N0 POBT HDR IVO

164 patients pT1-T2N0 Memorial Sloan-Kettering CC Local control 89% Cancer specific survival 85.6%

88.9% 79.4%

Ganly I et al. Long-term regional control and survival in patients with "low-risk," early stage oral tongue cancer managed by partial glossectomy and neck dissection without postoperative radiation: the importance of tumor thickness. Cancer 2013; 119:1168-76

259 patients with surgery (25% + EBRT) Princess Margaret Hospital Local control 78% Cancer specific survival 70.9% DFS 53%

34 pat. POBT (32% + EBRT) IVO .

80.9% 79.2% 69.6%

Goldstein DP et al. Outcomes of squamous cell cancer of the oral tongue managed at the Princess Margaret Hospital.. Head Neck 2013; 35:632-41

Same results with surgery and with perioperative BT, but better functional preservation