CPB Ljubljana 2018 course book

IS A BOOST DOSE BY ENDOCAVITARY BT OF PROGNOSTIC SIGNIFICANCE?

• Rotterdam: 72 patients ➢ Neoadjuvant CT

➢ 34 T1-2 N+ 70Gy + BT11Gy (3 x 3.66) ➢ 38 T3-4 N0 70Gy + stereotactic RT

• Amsterdam 76 patients ➢ 40T1-2 36 T3-4

➢ Concomitant CT + 70 Gy RT no boost • Local failure T1-2 with BT boost 0% without boost

14% (p=0.023)

T3-4 with boost (BT o stereotactic) 10%

without boost 15% (p=0.46)

Levendag P. Local control in advanced cancer of the nasopharynx: is a boost dose by endocavitary brachytherapy of prognostic significance? Brachytherapy 2013; 12:84-9