IMRT

3D vs IMRT: LUNG

V10: 45 vs 38 (p<0.01) ( IMRT benefit 7- 10% ) V20: 35 vs 25 (p<0.01) (IMRT benefit 7- 10%) MLD 19 vs 17 Gy NTCP: 36 vs 9% (Burman);13 vs 7% (Hyman)

41 pts Stage IIIA-IIIB PTV: 623cc (75-1645) Upper location

Murshed IJROBP 2004

Node - Node +

V20: 25.6 vs 23.6% 36.3 vs 23.6% 15% ) MLD: 15.3 vs 15.4 Gy 21.5 vs 15.4 V10: IMRT benefit 1.6% V20: IMRT benefit 8% V30: IMRT benefit 8.9%

Grills IJROBP 2003

( IMRT benefit ≈

Stage I-IIIB 10 pts

Liu IJROBP 2004