PracticeUpdate Oncology Best of 2018

Your aplastic anaemia (AA) patient could also be your PNH patient 1

• A diagnosis of AA may not be the full picture 1 • Up to 1 in 4 AA patients has a PNH clone detected 2 • PNH clone size can increase rapidly and unpredictably over time in patients with AA 2 • Regular PNH screening of AA patients is essential 3

PNH: Paroxysmal Nocturnal Haemoglobinuria References: 1. Schrezenmeier H, et al. Haematologica. 2014;99:922- 929. 2. Movalia M, et al. Poster 0886. Presented at the 17th Congress of the EHA, June 2012, Amsterdam, The Netherlands. 3. Killick SB, et al. BJH. 2016, 172, 187–207. © 2018 Alexion Pharmaceuticals Australasia Pty Limited. All rights reserved. Alexion Pharmaceuticals Australasia Pty Limited. ACN 132 343 036. Suite 401, Level 4, Building A, 20 Rodborough Rd, Frenchs Forest, NSW 2086 Australia. September 2018. AU/SOL-P/18/0033