11 Lip and buccal mucosa

Lip and buccal mucosa

9

THE GEC ESTROHANDBOOKOF BRACHYTHERAPY | Part II Clinical Practice Version 1 - 10/05/2019

Table 1: Local recurrence rate in lip carcinoma, LDR series [28-29-30-31-32-33-34-35-36]

Author [reference]

Year

Number

T

Isotope

Local recurrence

Gerbaulet (28)

1978

316

T1-4

Ra-Ir

4.2%

Pigneux (29)

1979

91

Ir

4.5%

Mazeron (3)

1983

1267

T1-4

Ir

3.4%

Cowen (30)

1990

248

Ir

4%

Orecchia (31)

1991

47

T1-2

Ir

6.4%

Van Limbergen (27)

1993

2794

T1-4

Ir/Cs

6%

Gerbaulet (7)

1994

231

Ir

5.6%

Beauvois (16)

1994

237

T1-4

Ir

5%

Fongione (32)

1994

69

T1-3

Ir

1.5%

Farrus (26)

1996

72

T1-3

Ir

11%

Tombolini (21)

1998

57

T1-3

Ir

10%

Arribas (33)

1998

99

T1-4

Ir

5%

Conill (34)

2007

54

T1-2

Ir

2%

Guibert (35)

2011

172

T1-2

Ir

9.9%

Río (36)

2013

89

T1-3

Ir

5%

Table 2: Local recurrence rate in lip carcinoma, series with PDR and HDR

Author [reference]

Year

Number modality

T

Fractionation Total dose

EQD2

Local failure

Johanson (22)

2011

43 PDR

T1-3

0.83 Gy

55-60Gy

49.4-53.9Gy

6%

Serkies (23)

2013

32 PDR

T1-4

1 Gy

60-70Gy

55-64Gy

3,5%

Guinot (24)

2003

39 HDR

T1-4

8/9x5-5.3 Gy

40.5-45Gy

54-56.2Gy

10%

T1-3 basal cell

Finestres (37)

2005

28 HDR moulds

1.8Gy

65-75Gy

63.7-74Gy

0

Lebioda (38)

2005

24 HDR

5.8 Gy

35Gy

45.8Gy

12.5%

100 LDR 21 HDR 70 LDR 33 HDR

60-70Gy 45-50Gy

Querejeta Ayerra (39)

2010

T1-4

4.5-5 Gy

54.4-62.5Gy

10%

Ghadjar (40)

2012

T1-2

4-5 Gy

7%

Guinot (4)

2013

104 HDR

T1-4

4.5-5 Gy

40.5-45Gy

48.9-56.2Gy

4.8%

Mut (41)

2016

68 HDR

T1-2

4.5-5 Gy

40.5-45Gy

48.9-56.2Gy

3.1%